A vesicle is a small elevated blister or sac filled with a ___________, located within or directly below the epidermis:

A vesicle is a small elevated blister or sac filled with a ___________, located within or directly below the epidermis:

• A. Red fluid
• B. Dense fluid
• C. White fluid
• D. Clear fluid

Answer: (D)

A vesicle is a tiny blister that contains clear fluid. This fluid is essentially serum that has collected between or just beneath the layers of the epidermis, so the lesion sits superficially on or directly under the outer skin. Because the fluid is clear, it differentiates vesicles from other fluid-filled lesions that contain colored or purulent material. If the contents were red, you’d think of a hemorrhagic or blood-filled lesion; if they were white and opaque, you’d expect pus or a thick inflammatory discharge. Vesicles are characteristically smaller than bullae; when a fluid-filled blister becomes large, it’s typically called a bulla instead. So the description precisely matches a vesicle: a small elevated blister filled with clear fluid located within or just below the epidermis.

A vesicle is a tiny blister that contains clear fluid. This fluid is essentially serum that has collected between or just beneath the layers of the epidermis, so the lesion sits superficially on or directly under the outer skin. Because the fluid is clear, it differentiates vesicles from other fluid-filled lesions that contain colored or purulent material. If the contents were red, you’d think of a hemorrhagic or blood-filled lesion; if they were white and opaque, you’d expect pus or a thick inflammatory discharge. Vesicles are characteristically smaller than bullae; when a fluid-filled blister becomes large, it’s typically called a bulla instead. So the description precisely matches a vesicle: a small elevated blister filled with clear fluid located within or just below the epidermis.